Slides and videos are available below. If the link is present but the file not found, the file will be uploaded soon. If however *the link* is not present: that file will never become available (sometimes due to legal restrictions that apply to the speaker).
Pictures of the event can be found here.
Monday the 1st of December, Philips Research (eScience Support) is organizing a symposium themed 'eScience in Industry'. In multiple scientific fields people are struggling with handling large datasets, secure connections, large simulation times, distributed datasets etc. This asks for a new way of working and the term eScience is used to describe the kind of science that need this new way of working. The talks will show how pharma and biomolecular science have become eScience. Further, 2 speakers from eScience centres located in the United Kingdom will share their ideas on eScience.
The symposium is held on the occasion of the opening for BiG Grid (see http://www.biggrid.nl) at the High Tech Campus, Eindhoven, The Netherlands. Because around that time part of Big Grid will be physically located here at the Campus and is planned to be fully operational.
Gridforum Nederland is the association for everyone in The Netherlands who is interested in or works with gridtechnology - from user to supplier, from scientist to policy maker. The organization offers a platform for the exchange of knowledge, expertise and information on this technology and all possible applications it enables.
eScience Support is the new name for the non-generic IT department of Philips Research ICT. It is there specifically for researchers, delivering Scientific and Engineering IT.
Attending the BiG Grid Opening is free, but does require registration.
Registration is open to everyone.
Location
The BiG Grid Opening will be at Philips Research at the High Tech Campus in Eindhoven (building: High Tech Campus 34). Click here for a route description and a High Tech Campus map. The program starts at 12:30 and ends at 17:00, with a moment to socialize from 15:40 to 17:00, so please stay for a drink afterwards.
Programma
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12:30 |
13:00 |
BiG Grid: eScience in Industry will be opened by:
Prof.dr. H.J. van den Herik (Jaap)
Prof.Dr. E.H.L Aarts (Emile) |
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13:00 |
13:30 |
Michael Simmons |
Developing and supporting eScience at the University of Cambridge |
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13:30 |
14:00 |
Jacob de Vlieg |
The Role of High Performance (Grid) Computing to Drive Innovation in Pharma |
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14:00 |
14:30 |
Break |
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14:30 |
15:00 |
Graham Cameron |
Bioinformatics: "e" is for "essential" in Biomolecular eScience |
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15:00 |
15:30 |
Jano Van Hemert |
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15:30 |
15:40 |
Wrap up |
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15:40 |
17:00 |
Socialize |
Drinks |
Presentations
BiG Grid Opening
Introduction
PDF | ODP | Powerpoint | WMVMovie: What Does It Take To Get 206 Blue Lights For BiG Grid?
A fast motion video on how the Philips Research part of BiG Grid was built up. If you are unable to play the file, please use VideoLAN - VLC media player (open source).
MPGJaap van den Herik
PDF | ODF | Powerpoint | WMVEmile Aarts
PDF | ODF | Powerpoint | WMVOfficial opening BiG Grid (videocall to computer room)
WMV
Developing and supporting eScience at the University of Cambridge
In this presentation I'll discuss the past and present projects and future plans for the eScience Centre at the University of Cambridge, with case studies showing successes, and lessons learnt. I'll discuss the project development process, highlighting the importance of working directly with individual researchers, and of collaboration with industry.
Michael Simmons
- Development Director at the Cambridge eScience Centre
"I am the point of contact for anyone, either within the University or outside, who is interested in our work, in potential collaboration or in making contacts in the area of scientific computing. I support the development of research proposals, help find funding, develop links with companies and co-ordination of projects when underway.
I've been working in the area of research project support since 2000, first at the University of Kent, where we developed a programme to send mostly computer science undergraduates to the US and UK to work in Sun Microsystems as part of their degrees. I then worked in the Kent University Enterprise Unit, as regional development manager, and later as business projects manager at Queen Mary College, University of London before coming to Cambridge.
My first project at Cambridge was co-ordinating the development of a semantic web repository (the National Transport Data Framework) and also supporting the Cambridge part of the urban pollution sensing project, MESSAGE.
I am a PIPSS Fellow in the University of Cambridge for the STFC funding council, helping to develop links between colleagues in STFC-funded areas and elsewhere, including potential commercial opportunities.
I'm a Cambridge Enterprise Champion, one of a number of volunteers in faculties who can advise colleagues on consultancy and commercialisation through Cambridge Enterprise.
My background before 2000 is some ten years in office network management, Novell and NT along with academic course management; office network training and English language teaching. I have degrees in history and in computing."
Unfortunately Michael Simmons was not able to make it to the event.
He apologizes to all visitors and other speakers.
He did make available his presentation, so download the presentation: PDF | ODP | Powerpoint
The Role of High Performance (Grid) Computing to Drive Innovation in Pharma
Bioinformatics and high performance computing technologies are well-established scientific disciplines in pharmaceutical research. The availability of complete genome sequences and vast amounts of structural information on drug targets and target-ligand complexes have stimulated many efforts to rationalize the drug design process.
It is believed that genomics and informatics may create many opportunities to speed up the multidisciplinary drug discovery process, and provide novel approaches to the design of drugs otherwise not possible. However, low productivity and high late stage attrition continue to challenge the pharmaceutical industry. Information systems across Discovery and Clinical Research are attempting to integrate heterogeneous data sources and even cultures in an attempt to increase productivity and improve success rates. New integrated computing technologies are needed to address the attrition problem and to increase productivity.
Jacob De Vlieg
- Global Head Drug Design & Informatics- Schering Plough Corporation
- Head Computational Drug Discovery - Center of Molecular and Biomolecular Informatics, Radboud University, Nijmegen, the Netherlands)
Prof. Dr. Jacob de Vlieg studied biochemistry and biophysics at the State University of Groningen and graduated cum laude. During his Ph.D. research he developed computer simulation techniques to determine tertiary protein and DNA structures from Nuclear Magnetic Resonance (NMR) spectroscopy data. Hereafter he joined the Bioinformatics group of Prof. P. Argos at the EMBL (European Molecular Biological Laboratory), Heidelberg as staff scientist to develop structural bioinformatics techniques for the prediction of three dimensional (3D) structures of virus proteins.
From 1990 until 2001 dr. de Vlieg held a range of research and management positions at Unilever Research in the field of molecular science informatics, biophysics and ICT. Appointed in 2000, he is currently part-time professor Computational Chemistry at the CMBI (Centre for Molecular and Biomolecular Informatics), Radboud University, Nijmegen. His research interests centre on structural bioinformatics, translational medicine and genomics-based drug design.
Dr. de Vlieg joined NV Organon in 2001 as head of the Department of Molecular Design and Informatics (MDI). The overall MDI goal is to enable information-driven R&D. Key MDI skill bases include computational medicinal chemistry, structure-based drug design, bioinformatics, systems biology, microarray platform technologies, pharmacogenetics and design and delivery of integrated information systems for Discovery Research and Non-Clinical.
In 2006 he was appointed as CIO Research and Development Organon with the task to integrate IT -in all its manifestations- into a global integrated R&D process. A key challenge is to drive innovation by bridging Research and Development through the concept of translational medicine.
In 2008 he is appointed as Global Head Drug Design & Informatics, Schering-Plough, to support the Discovery Research and Early Clinical Research & Experimental Medicine functions.
Prof. de Vlieg serves on a number of advisory boards and committees, including membership of the NCF board (Netherlands National Computing Facilities Foundation), IT board CTMM (Center for Translational Medicine), BioGrid board (the Dutch e-science grid-based infrastructure), Netherlands Genomics Pre-seed Fund, and the KNAW (Royal Netherlands Academy of Arts and Sciences) Research Foresight Committee "Mathematics in Life Sciences".
Download the presentation:
PDF |
ODP |
Powerpoint
Or watch it on video:
WMV
Bioinformatics: "e" is for "essential" in Biomolecular eScience
Over the space of three decades, biologists have accumulated a wealth of detailed information about the molecular components of living systems and their behaviour. Early painstaking efforts which revealed fragmentary information about genes and their products have been dwarfed by the systematic sequencing of whole genomes, and even the ground-breaking human genome project looks modest by today's efforts to sequence thousands of genomes. Ever more ingenious high-throughput methods have generated shared information collections of sequences, structures, molecular interactions, and gene-expression profiles (to name just a few).
This shared electronic record of science is essential to any research which touches living systems. The obvious relevance to human health and medicine is but one facet of its utility. Dozens of industries ranging from fish farming through brewing to even timber production optimise their benefits by studying the genetic make-up of their subject matter.
However, exploiting the shared electronic knowledge requires careful information engineering. The volume of information is very substantial, challenging storage capabilities, and its complexity is mind-boggling. Millions of molecules interact in the processes that control even a single cell.
With many collaborators, we at the European Bioinformatics Institute are long-standing custodians of many key biological information collections. Our methods for information collection, organisation and sharing have tracked rapid developments in informatics, not least in the era of eScience. In this talk I will present some of that history, the challenges that have arisen, and the solutions adopted. I will rejoice in the emergence of eScience as a unifying theme bridging disciplines, sharing solutions, and legitimising the nameless profession which had evolved to tackle our information needs. In discussing the developments in bioinformatics I will speculate beyond today's eResearch to possible future scenarios for information sharing and exploitation.
Graham Cameron
- European Bioinformatics Institute (EBI) Associate Director)
Graham is currently Associate Director of the European Bioinformatics Institute.
Previously he has been Joint Head with Michael Ashburner. He was responsible for the launch of the Institute in 1993 and ran the Information Services of the EBI until 1998. Earlier, Graham worked with EMBL-Heidelberg in the DNA Data Library, first in software and database design, and then leading the project from 1986.
Graham has undertaken a degree and postgraduate research in Psychology and Computer Science, with ancillary studies in Physics and Mathematics. He has held various posts in academic computation and data provision including databases on: primate behaviour, health information, social behaviour, and British economic behaviour.
| Graham Cameron | ||
| With the European Molecular Biology Laboratory and the EBI | Currently | Associate Director, the European Bioinformatics Institute |
| 1998-2001 | Joint Head of the European Bioinformatics Institute | |
| 1994-1998 | Head of Services for EMBL's UK Outstation, the European Bioinformatics Institute. Responsible for the service section of the Institute, providing a broad range of informatics services for molecular biological and biotechnological research. | |
| 1993-94 | Project Leader responsible for the launch of the EBI. | |
| 1986-92 | Manager, the EMBL Data Library. Providing biological information to researchers. | |
| 1983-86 | Database Administrator, EMBL Data Library | |
| 1982-83 | Applications Programmer, EMBL Data Library | |
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Previous Employment |
1981-82 | Computer Advisor, The University of Stirling, Scotland.. |
| 1979-81 | Applications Programmer, ESRC Data Archive, The University of Essex, England. | |
| 1979 | Database designer, Forth Valley Health Board. | |
| Education | 1976-79 | Research Assistant (Primate Behaviour) the University of Stirling. |
| 1973-76 | Research Studentship at the University of Stirling (Psychology of Learning) | |
| 1969-73 | B.A. Honours in Psychology, Physics, Mathematics and Computer Science, University of Stirling, Scotland. | |
Download the presentation:
PDF |
ODP |
Powerpoint
Or watch it on video:
WMV
National e-Science and Local e-Research
The UK e-Science programme started in 2000 and has to date funded over 100 projects together worth more than £250 million. A major component of its success is its Core Programme that served as the basis for the UK's e-Science activities. I will show the evolution of this programme and highlight a number of its generic activities, which may serve as entry points to scientists wishing to engage the e-Science community and make use of its services. e-Research is all about the invention of computer-enabled methods and their application to research. I will showcase a number of local projects that capture this spirit.
Jano Van Hemert
- Research Leader and Co-Theme Leader National e-Science Centre (NeSC) Edinburgh
He has held research positions at the Leiden University (NL), the Vienna University of Technology (AUT) and the National Research Institute for Mathematics and Computer Science (NL). In 2004, he was awarded the talented young researcher fellowship by the Netherlands Organization for Scientific Research. Many of his research projects have included partners from industry.
His research output includes over fifty published papers (http://www.vanhemert.co.uk/publications/) and software on optimisation, constraint satisfaction, evolutionary computation, data mining, scheduling, problem difficulty, dynamic routing, adaptive methods, Grid computing, and e-Science applications.
Download the presentation:
PDF |
ODP |
Powerpoint
Or watch it on video:
WMV
Register
Registration opened on 16 October 2008
Registration closed on 01 December 2008
List of people that registered
serge point vrijaldenhoven apetail philips dot com